Drug-resistant “superbugs” infect 2.8 million people and cause more than 35,000 deaths each year, underscoring the enormous public health threat of germs in what one official describes as a “post-antibiotic era,” according to a new Centers for Disease Control and Prevention report.

The report, which analyzes electronic health records and other data, shows an infection every 11 seconds and a death every 15 minutes on average from bugs that resist treatment from antibiotics. The CDC said there are nearly twice as many deaths from antibiotic-resistant infections compared to the agency’s 2013 report, which likely underestimated the numbers.

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